What is the problem associated with multimorbidity?

• A. It reduces risk of polypharmacy
• B. More diseases increase imbalance, progressive frailty and mortality, and increased risk for polypharmacy and associated complications
• C. It eliminates the need for regular medical follow-up
• D. It improves resilience

Answer: (B)

Multimorbidity means living with more than one chronic condition, and that combination makes care more complex. Each condition can require medications and interventions that interact with others, creating imbalances in treatment and health status. As the number of diseases grows, the likelihood of conflicting treatments, adverse drug effects, and functional decline increases. This also raises the risk of polypharmacy—taking multiple medications—which brings its own complications, such as adverse drug events, drug–disease interactions, nonadherence, falls, and hospitalizations, all contributing to higher mortality.

So this option best captures the problems associated with multimorbidity: more diseases lead to greater imbalance, progressive frailty, and mortality, along with an increased risk for polypharmacy and its complications. The other statements don’t fit because multimorbidity does not reduce polypharmacy; it typically increases it. Regular medical follow-up is not eliminated—in fact, ongoing monitoring is essential to manage multiple conditions. And resilience is not improved by multimorbidity; it tends to be diminished due to frailty and cumulative health burdens.