Which of the following is NOT one of Fried's frailty criteria?

• A. Low grip strength
• B. Slow walking speed
• C. Unintentional weight loss
• D. High physical activity

Answer: (D)

Fried's frailty phenotype defines frailty by five specific criteria: unintentional weight loss, self-reported exhaustion, weakness measured as low grip strength, slow walking speed, and low physical activity. A person is considered frail if they meet three or more of these criteria, and they’re not frail if they meet fewer than three. High physical activity is not among these criteria; it is the opposite of the low physical activity component and is associated with robustness rather than frailty. So, identifying high physical activity as a criterion would not fit Fried's framework. The other indicators—unintentional weight loss, slow walking speed, and weak grip strength—are all part of the five criteria and help signal frailty when present.